Peptides and Antibiotic Resistance

Several studies by various respected research institutions have shown how it is possible for bacteria to adapt and become immune to antibiotics. There is one particular study which was ranked by the United Nations to be in the same level as Ebola and HIV. Another study was commissioned in the United Kingdom which revealed that in the absence of new antibiotics, millions of lives would be lost due to bacterial infections by the year 2050.

To help in increasing the options for combating infectious diseases, scientists are now considering the use of natural proteins, known as antimicrobial peptides in combating antibiotic resistance. Other than killing bacteria, the antimicrobial peptides have the ability to kill other microbes such as viruses and fungus. Researchers at the British University of Columbia, University of Brasilia and MIT have come up with antimicrobial peptides which posses the potential to decimate different bacteria variants, especially those that have usually displayed strong resistance to most of the antibiotics.

One of the greatest concerns of MIT in these researches is to develop a solution for fighting antibiotic resistance and the use of peptides to achieve this purpose have been fascinating in the sense that peptides has offered a new possibility of overcoming such resistance. And with that, millions of deaths around the globe could be reduced, including those occasioned by various forms of cancer.

According to a study published in Scientific Reports, a peptide known as Clavanin-MO was discovered to have antimicrobial and immunomodulatory properties, and it has the ability to target the cell membranes and interrupt the functioning of the matter within, including the DNA and RNA. Additionally, they secrete a substance known as leukocytes which secrete certain chemicals to destroy microbes.

Currently, a lot of research is on going to try and find out the specific factors which make peptides have such powerful properties and it can only be hoped that conclusive results will soon be reached and the world will find a solution to combat antibiotic resistance.